Computational methods for stochastically modeled biochemical reaction networks

David Anderson (October 25, 2011)

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Abstract

I will focus on computational methods for stochastically modeled biochemical reaction networks. The simplest stochastic models of such networks treat the system as a continuous time Markov chain with the state being the number of molecules of each species and with reactions modeled as possible transitions of the chain. I will show how different computational methods can be understood and analyzed by using different representations for the processes. Topics discussed will be a subset of: approximation techniques, variance reduction methods, parameter sensitivities.