Dynamic-clamp studies of neuronal synchronization

John White (March 25, 2011)

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Abstract

Coherent neuronal activity is ubiquitous and presumably important in brain function. I will review my group's experimental studies of the mechanisms underlying coherent activity using dynamic clamp technology, which allows us to perform virtual-reality-inspired experiments in neurons in vitro. Using these techniques and mathematical tools from dynamical systems theory, we are trying to understand which factors give rise to stable neuronal synchronization in the presence of heterogeneity, noise, and conduction delays.